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Isomers of chiral molecules may differ in activity and toxicity; therefore, availability of isolated isomers is of significant importance to study their occurrences and fate in the health or environment.
The chromatography of chiral molecules is a simple and elegant technique for rapid isolation of enantiomers of high purity.
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This technique applies to the concerned agrochemicals, pharmaceutical products, amino-acids, biochemicals,… domains.
Daicel Corporation is the global market leader in enantioselective chromatography, offering the most extensive portfolio of chiral stationary phases available on the market.
Professor Yoshio Okamoto of Nagoya University in Japan invented polysaccharide-derived chiral stationary phases (CSPs) in the 1980s. Daicel Corporation commercialized Prof. Okamoto’s invention, which is the foundation of the highly successful and widely used Daicel CSPs, CHIRALCEL (cellulose) and CHIRALPAK (amylose) columns.
In the next generation, CHIRALPAK IA, IB, IC, ID, IE and IF columns, the stationary phase is immobilized on the packing material instead of the coating process used in Daicel’s original chiral columns. This process dramatically improves robustness and stability to mobile phase composition. There are currently no known organic solvents which will damage the CHIRALPAK IA, IB, IC, ID, IE and IF columns in any way.
The immobilized columns, CHIRALPAK IA, IB, IC, ID, IE and IF are available in 3, 5, 10 and 20 microns particle sizes for analytical and preparative separations. |
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