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Maintenance of your Jacketed Lab Reactor system. In this webinar we will cover how to perform routine checks and maintenance on your Jacketed Lab Reactor to ensure that you achieve efficient mixing, accurate temperature control and good sealing when performing your chemistry.
Are you running your overnight reactions unsafely? Lab control software can help you perform safe and efficient unattended reactions. In this webinar we will discuss how reactions can be data logged as well as safety feedback loops put in place to ensure that reactions can be left unattended overnight or longer by using lab control software.
When it comes to chemical reactions in both R&D and production processes, achieving the right temperature is crucial. In this webinar we will be joined by Dr Paddy Delaney from Huber to discuss the factors that influence temperature control when using jacketed lab reactors as well as advice on how to improve the performance of your system.
Join us to discuss the benefits of overhead stirring on a small scale: Are you using magnetic or overhead stirring for small scale research and process development? What’s the difference and why does it matter? What factors can be affected when moving from magnetically stirred reactions to overhead and how might this help improve your chemical development and scale up?
Learn how the new Heidolph Distimatic Pro automates rotary evaporation processes on industrial scale (>20 L), completely eliminating the need for users to manually refill and empty flasks, for complete automated evaporation. In this webinar Ravi Hosein (Radleys) and Jurgen Heyder (Heidolph) will show you how the new Distimatic Pro and Reactor-Ready Pilot work in tandem for automated operation.
Are you using round bottom flasks with heating only equipment for your small-scale process development chemistry? Do you find these experiments don’t scale up as well as you would like? Let’s talk about what’s wrong with this traditional set up and what you can do to improve it.
When purchasing a jacketed lab reactor setup for scaling up your process, there are many considerations to be made. In this webinar we cover the fundamental points of specifying the right reactor and ancillary devices to ensure that you get the optimal performance of your jacketed lab reactor system for scale-up and process development.
We will discuss the importance of vacuum control in common lab applications, covering the different types of vacuum pumps used in the lab and best practices for using and maintaining them. We will also focus on rotary evaporation and how vacuum affects bumping and foaming of products, ways to mitigate these, plus tips to make your evaporation processes more efficient.
Do you require mechanical stirring on small scale reactions? E.g. viscous materials, heterogeneous mixtures, fragile solids? Join us to see the Tornado Overhead Stirring System in action. Save time and space for the overhead stirring of multiple reactions in round bottom flasks.
In this webinar we look at some considerations when designing a jacketed lab reactor system and their implications. We then follow on with some bespoke design options available for our jacketed reactors, where we review a variety of subjects including reactor geometry, thermal fluid connections, lid port design, drain valves and more illustrated with some examples of custom systems we have done for users.
When choosing the kit you will use for your Process R&D chemistry, there are many considerations to be made. If you’re currently using hotplates, ice baths and jacketed reactors for your small-scale Process R&D chemistry, how could you consolidate this work with a single piece of equipment? In this webinar we discuss the most common needs for process chemistry and introduce the Mya 4 Reaction station for screening reactions to small scale Design of Experiment.
Mark Radley shows you inside our glass blowing workshop for a live demonstration then on to a technical discussion on the bespoke design options for all Radleys reactors. *please note that due to a technical interruption the start is missing from the recording.
Rotary Evaporation principles explained In this webinar you’ll learn about the principles behind rotary evaporation, the basics of using a rotary evaporator, how to make your evaporations more efficient and also how to maintain your rotary evaporator to increase its life span.
Are you making the most of your hotplate? Louisa Quegan and Keren Abecassis share their chemistry lab hacks: showing you a range of tools you might not know about. From 1 position to 45 on a single hotplate – with working volumes between 0.5 ml and 2.5 L. Lou and Keren discuss their personal experience in the lab using traditional methods vs. this range of tools.
Taking you through the Mya 4 range using a live demonstration hands-on approach. Mya 4 is highly flexible reaction station with 4 independent zones for accurate temperature control and reaction optimisation.
This webinar will be a case study of a scale-up group, using an automated addition to control an exothermic reaction, and the use of safety feedback loops to pause and restart the addition based on process temperature. At this time of social distancing in our laboratories when we need to minimise the number of people in the lab, automation and data-logging can help.
An introduction to the range of productivity and parallel chemistry tools in the Radleys range with a live demonstration and hands on approach.
An in depth look at the Heidolph Distimatic, which automates rotary evaporators to remove bottlenecks to the solvent removal process. Including a full hands-on demonstration of the equipment.
With safer, cleaner and greener working practices high on the agenda for lab managers and user’s, we talk you through simple but effective changes you can make to improve the way you do your chemistry.
A hands-on walk through the Carousel 6 and 12 in detail. We look at all the tools and accessories in this range and then run through the operation and setup. We include information on using a Carousel, how to dry the system, running efficient reflux experiments and any necessary maintenance.
Watch ‘Introducing – Mya Reaction Station’ before you watch this. Once you’ve seen a demonstration of the Mya 4 Reaction Station, watch this to learn differences between the Mya 4 Control Pad and the PC control software and which one would suit your application best.
Accelerate your Process Research and Development with a flexible reaction station. In this webinar we’ll show you how to improve reproducibility and eliminate timewasted manually recording results with automated data logging. Mya 4 can be set up quickly: benefitting from flexible and versatile configurations, easily meeting the needs of different applications and projects.
Temperature controlled, stirred and contained filtrations – Radleys Reactor-Ready Filter Lab Reactor for crystallisations, reaction work-ups and product isolation
In this webinar we will explore the Radleys range of Reactor-Ready filter vessels, demonstrate how to assemble and use the filter reactor as well as discuss potential applications.
Good practices to achieve consistency in process scale up Scaling up chemical reactions can present a number of challenges with respect to efficient mixing, mass transfer, controlling exothermic reactions, heat transfer and reaction kinetics.
Reaction optimisation is a key component across the pharmaceutical development cycle. From early-stage small library production to full scale manufacturing, optimising a reaction for the desired outcome can be a difficult and time-consuming exercise.
Key to solving these challenges is defining the correct input parameters, the correct product attributes, and therefore the correct tools to achieve these.
In this short webinar we will discuss these parameters and look at some customer examples to highlight the points raised and how these were addressed using the tools that Radleys was able to offer.
In this webinar we will discuss the benefits of crystallisation as a tool for product isolation, versus other common techniques.
We will look at the methods of performing crystallisations used by chemists, with examples, including cooling, anti-solvent, pH adjustment and reactive crystallisations. There will be discussion of the Meta Stable Zone (MSZ) and use of phase diagrams.
Finally, we will discuss what equipment is most effective for performing crystallisations along with some tips to improve your crystallisation processes.
Scaling up exothermic additions in the lab
Adding liquids to a reaction mixture is integral to synthetic chemistry. Scaling up from ml to L will often require changes in how these additions need to be made.
From initiating a reaction, quenching, or adding antisolvent as part of a crystallisation, we need to consider consistent and reproducible dosing.
A chemist may face issues with containment, holding temperature of feed stock, viscosity, mass and how to control highly reactive material.
Mixing of chemical reactions are often performed in two ways, magnetically or with mechanical agitation.
The key to good mixing is understanding the following parameters:
Reagent & solvent properties
Reactor design & geometry
Agitator design & geometry
Mixing pattern
It is often necessary for chemists to perform reactions at temperatures close to or below 0°C. In this webinar we will explore the theory of low temperature reactions (thermodynamics vs kinetics), the types of reactions that require cold temperatures and the challenges that chemists face when attempting to maintain low temperatures during reactions.
We also discuss some tips on maximising the performance of cold reactions versus the traditional methods as well as some considerations when scaling up.
Chemistry labs are amongst the most intensive consumers of energy and water. In this webinar, we look at where these resources are being used in university labs and identify areas that can be affected by individual scientists and groups. Water-cooled condensers and heating equipment are some of the worst culprits, so we discuss the issues and look at some improvements and alternatives that can be used to dramatically cut water and energy waste.
The discussion is driven by data from ourselves, universities, and non-profit environmental groups.
Chemistry labs are amongst the most intensive consumers of energy and water. In this webinar, we look at where these resources are being used in university labs and identify areas that can be affected by individual scientists and groups. Water-cooled condensers and heating equipment are some of the worst culprits, so we discuss the issues and look at some improvements and alternatives that can be used to dramatically cut water and energy waste. The discussion is driven by data from ourselves, universities, and non-profit environmental groups.
In our latest webinar ‘Case Studies in Catalysis – Success Stories and Tips for More Efficient Reactions’ we will share success stories and tips for more efficient catalysis. We will discuss a range of topics including how catalysis is cleaner and greener, solid supported catalysts, and working up multiple reactions with ease.
Using highlights from previous webinars, this webinar will focus on the Reactor-Ready jacketed lab reactor, its benefits, and practical applications. Key topics include: the advantages of jacketed lab reactors, considerations when scaling up including temperature and agitation method, and different vessel types. We will also show how easy it is to swap between vessels, enabling quick scalability.
In this technical webinar our hosts explore and discuss the importance of developing a good crystallisation process for Active Pharmaceutical Ingredients (API). Crystallisation can pose a significant risk to the success of a drug; however, the risks can be mitigated with an comprehensive understanding of the process, using process analytical technologies (PAT).
Join us as we discuss the correct positioning of different laboratory probes in our Reactor-Ready and Mya 4 Reaction Station. Proper positioning of rigid probes is crucial for accurate process analytics. We will explain the importance of probe placement and its impact on measurement accuracy. We will present solutions for probe positioning using temperature PAT, pH, and conductivity probes, including compound angled ports in PTFE lids. Radleys has worked in conjunction with BlazeMetrics to design and optimise PTFE lids specifically for use with the Blaze probes.
Join us for a webinar on the Mya 4 Automated Reaction Station, a cutting-edge solution for process development and scalability. As we look back at previous webinars, discover how this compact unit offers unparalleled control and ease of use for optimising chemical reactions. Learn about the features and benefits of the Mya 4 Reaction Station, including its four independent temperature-controlled zones, active cooling, and scalability mimicry. Explore its user-friendly interface and compatibility with various reaction vessels.
In this webinar we introduce Reactor-Reactor Flex, a modular jacketed lab reactor system that allows users to choose the features that suit their budget and application. We discuss how to use the online configurator to build a system from component parts as well as describing the pre-configured packages that are available. We will also have a hands-on demonstration of the system showing the new components.
The Webinar focuses on Xelsius Accessories such as the Inert Workstation, the Dosing Station and the Pressurized Vessel. These accessories are designed to give Xelsius more flexibility and enhance your user experience, allowing you to achieve even greater results with Xelsius. Learn more about their functioning by watching our Webinar.
